Sildenafil: MedlinePlus Drug Information
Viagra (sildenafil) is a prescription medication used to treat erectile dysfunction. Headache, flushing, and upset stomach are common Viagra side effects. These effects are usually mild and often resolve on their own. While rare, Viagra can cause an erection that lasts longer than 4 hours (priapism). Sildenafil, commonly known as Viagra, is a popular medication for erectile dysfunction (ED) in men. Many men who take this medication may wonder if it is safe to what is viagra do Viagra (sildenafil) is a brand-name prescription drug that s used to treat erectile dysfunction (ED). Learn about side effects, warnings, dosage, and more. Sildenafil may be used to treat erectile dysfunction (ED or impotence) in men (Viagra brand) or pulmonary arterial hypertension in both men and women (Revatio Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, sildenafil works by increasing blood flow to the
The pharmacokinetic characteristics of tadalafil, with its 17.5-hour half-life, make it suitable for daily dosing and achieving a steady-state serum concentration. Recently, udenafil Tadalafil, as a selective phosphodiesterase type 5 (PDE5) inhibitor, can be rapidly absorbed with a half-life of 17.5 hours. 6 Some clinical trials followed up for 12 tadalafil half life chart Notably, tadalafil has an elimination half-life of 17.5 h, considerably longer than the half-lives of the other drugs in this class (i.e, sildenafil [3 5 h] and vardenafil [4 5 h]) (1,16,17). With respect to metabolism, no active metabolites of tadalafil have been identified. Tadalafil is excreted In patients with pulmonary hypertension not receiving concomitant bosentan, the mean oral clearance for tadalafil is 1.6 L/hr, and the mean terminal half-life is 35 hours. Tadalafil is excreted predominantly as metabolites, mainly in the feces (approximately 61% of the dose) and to a lesser extent in the urine (approximately 36% of the dose). Half-life. The mean half-life of elimination of tadalafil is .5h in healthy adults. 1,7,8 The mean half-life of elimination in adults with PAH is reported as 35h. 8. Clearance. The
